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Filtered Search Results
Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000807576 D-VAL-LEU-LYS-PNA 10MG
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BIOHIPPO InVivoMAb Anti-Human ARG1/Arginase-1 Antibody (Iv0120), 100 µg
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ARG1/Arginase-1 Recombinant Antibody (clone Iv0120) is a recombinant Mouse IgG2a, kappa antibody specific for ARG1/Arginase-1. It reacts with Human. Suitable for ELISA, FCM, Neutralization. Recombinant production ensures high specificity and lot-to-lot reproducibility. Supplied as 100 ug.
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Ambeed AMBEED
5000892033 BOC-VAL-CIT-PAB-PNP 100MG
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Medchemexpress LLC Mal-peg2-val-cit-paba-pnp | 1345681-52-8 | 96.8% | 755.73 | C34H41N7O13 | 25 MG
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Mal-PEG2-Val-Cit-PABA-PNP is a cleavable antibody-drug conjugate (ADC) linker used to attach cytotoxins to antibodies during ADC synthesis. It contains a maleimide reactive group for thiol conjugation, a PEG2 spacer to improve solubility, a cathepsin-cleavable valine-citrulline dipeptide, and a self-immolative p-aminobenzyl spacer with a p-nitrophenyl leaving group.
- Cleavable linker for antibody-drug conjugate synthesis.
- Maleimide functional group enables thiol reactivity.
- Peg2 spacer increases aqueous solubility and hydrophilicity.
- Val-Cit dipeptide is cleavable by lysosomal proteases.
- PABA self-immolative spacer allows efficient payload release.
- PNP leaving group facilitates conjugation chemistry.
- Available in multiple small-scale pack sizes for research use.
- Store protected from light and under inert gas for stability.
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Medchemexpress LLC DBCO-Val-Cit-PABC-PNP | 2994332-18-0 | 859.92 | C46H49N7O10 | 10 MG
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DBCO-Val-Cit-PABC-PNP is a cleavable antibody-drug conjugate (ADC) linker containing a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) and a Val-Cit-PABC protease-cleavable spacer. It is supplied as a solid reagent for research use in ADC synthesis.
- Contains DBCO for copper-free SPAAC click chemistry.
- Protease-cleavable Val-Cit-PABC spacer for enzyme-triggered payload release.
- Molecular weight 859.92 and formula C46H49N7O10.
- Available in small pack sizes suitable for synthesis, including 10 mg.
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Medchemexpress LLC Azido-peg3-val-cit-pab-pnp | 2055047-18-0 | MFCD30527416 | 99.1% | 773.79 | C34H47N9O12 | 10 MG
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Azido-PEG3-Val-Cit-PAB-PNP is a cleavable three-unit PEG linker bearing an azide functional group, designed for use in bioconjugation and the synthesis of antibody-drug conjugates and PROTACs. It contains a protease-cleavable Val-Cit dipeptide and a para-aminobenzyl spacer with a PNP leaving group, enabling enzymatic payload release and click-based conjugation.
- Cleavable Val-Cit-PAB motif for enzyme-triggered payload release.
- Azide functional group compatible with CuAAC and SPAAC click reactions.
- Three-unit PEG spacer improves solubility and flexibility in conjugates.
- Available in small laboratory quantities for synthetic applications.
- High reported purity suitable for bioconjugation workflows.
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Medchemexpress LLC Acetylene-linker-Val-Cit-PABC-MMAE | 1411977-95-1 | 95.2% | 1307.62 g/mol | C67H106N10O16 | 10 MG
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Acetylene-linker-Val-Cit-PABC-MMAE is an antibody-drug conjugate (ADC) linker-payload conjugate that couples an alkyne-bearing cleavable Val-Cit-PABC linker to the tubulin inhibitor MMAE. The acetylene handle enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation, while the Val-Cit-PABC motif permits proteolytic release of the payload after internalization.
- Contains an alkyne handle for CuAAC click chemistry
- Val-Cit-PABC motif enables proteolytic release of MMAE
- Provides a cleavable linker-payload architecture for ADC development
- Molecular formula C67H106N10O16 and molecular weight 1307.62 g/mol
- Typical purity approximately 95.2%
- Supplied as a 10 mg sample; store at 4°C under inert atmosphere
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Medchemexpress LLC Mal-amide-PEG8-Val-Ala-PAB-PNP | 2210247-59-7 | 95.7% | 1033.08 | C48H68N6O19 | 25 MG
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Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable antibody-drug conjugate (ADC) linker used to attach cytotoxic payloads to antibodies and enable enzymatic release inside target cells. It combines a maleimide reactive group, a PEG8 spacer, a Val-Ala protease-cleavable dipeptide, a para-aminobenzyl self-immolative spacer, and a p-nitrophenyl carbonate leaving group.
- Cleavable by proteases to enable intracellular payload release.
- Maleimide group enables thiol conjugation to antibody cysteines.
- PEG8 spacer improves solubility and linker flexibility.
- High purity suitable for research bioconjugation (~95.7%).
- Available in small mg-scale packs for laboratory conjugation workflows.
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Medchemexpress LLC Fmoc-val-cit-pab-duocarmycin | 99.4% | 1050.59 g·mol⁻¹ | C58H60ClN7O10 | 1 MG
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Fmoc-Val-Cit-PAB-Duocarmycin is a drug-linker conjugate intended for use in antibody-drug conjugate (ADC) research. It couples a Duocarmycin payload to an Fmoc-Val-Cit-PAB cleavable linker, and is supplied as a solid with reported high purity and defined storage conditions.
- High purity (99.44%).
- Molecular weight 1050.59 g·mol⁻¹.
- Molecular formula C58H60ClN7O10.
- Solid form, white to yellow.
- Storage: powder -20 °C; in solvent -80 °C for 6 months or -20 °C for 1 month.
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Medchemexpress LLC Fmoc-val-ala-aminomethyl acetate | 2505045-86-1 | 97.3% | 481.54 | C26H31N3O6 | 1 G
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Fmoc-Val-Ala-aminomethyl acetate is a valine-alanine protease-cleavable linker reagent used in the synthesis of antibody-drug conjugates (ADCs) for research applications. It is characterized by LCMS-reported purity and is used to introduce a cleavable spacer between antibody and payload in linker-drug constructs.
- Protease-cleavable valine-alanine linker.
- Suitable for ADC synthesis and linker-drug conjugation.
- Purity 97.3% (LCMS).
- Molecular weight 481.54 g/mol.
- Molecular formula C26H31N3O6.
- Supplied as a 1 G pack for research use.
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STA PHARMACEUTICAL US LLC Fmoc-N-methyl-L-norvaline | 10 g | CAS 252049-05-1 | MDL MFCD01861326
Fmoc-N-methyl-L-norvaline is a Amino Acid reagent (Subcategory: N-Me AA) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 252049-05-1
- MDL: MFCD01861326
- InChIKey: HKELUUGCKFRJQM-IBGZPJMESA-N
- Molecular Weight: 353.418
- Molecular Formula: C21H23NO4
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid
- SMILES: CCC[C@H](N(C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C)C(O)=O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STA PHARMACEUTICAL US LLC Fmoc-L-IsoValine-OH | 1 g | CAS 857478-30-9 | MDL MFCD12031688
Fmoc-L-IsoValine-OH is a Amino Acid reagent (Subcategory: Alpha-alkylated) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 857478-30-9
- MDL: MFCD12031688
- InChIKey: DZSLHAJXIQCMLR-FQEVSTJZSA-N
- Molecular Weight: 339.391
- Molecular Formula: C20H21NO4
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-methylbutanoic acid
- SMILES: CC[C@@](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)(C)C(O)=O
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Mc-val-cit-pab-clindamycin | 1639793-13-7 | 100.0% | 1016.08 g/mol | C46H72Cl2N8O11S | 5 MG
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MC-Val-Cit-PAB-clindamycin is a drug-linker conjugate used in antibody-drug conjugate (ADC) research that links the protein-synthesis inhibitor clindamycin to a cleavable Val-Cit-PAB linker, producing a payload module with reported antitumor activity.
- High reported purity: 99.99%.
- Chemical formula: C46H72Cl2N8O11S.
- Molecular weight: 1016.08 g/mol.
- Intended for ADC research and preclinical evaluation.
- Supplied as a 5 mg pack.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Dmba-sil-mal-mmae | 2923885-49-6 | >98.0% | 1403.65 | C72H106N8O20 | 10 MG
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A cytotoxin-linker conjugate pairing the antimitotic agent monomethyl auristatin E (MMAE) with a DMBA-SIL-Mal linker for use in antibody-drug conjugate (ADC) research, synthesis, and analytical characterization.
- Contains monomethyl auristatin E (MMAE) tubulin inhibitor payload.
- Designed for ADC synthesis and analytical characterization.
- Available in multiple research-scale sizes, including 10 mg.
- Recommended storage: sealed at -20°C; in solvent, -80°C for long-term storage.
- Molecular weight 1403.65 and molecular formula C72H106N8O20.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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STA PHARMACEUTICAL US LLC Fmoc-3,4-dehydro-L-Val-OH | 5 g | CAS 1932087-73-4 | InChIKey KSDLNKHXKRYOST-SFHVURJKSA-N
Fmoc-3,4-dehydro-L-Val-OH is a Amino Acid reagent (Subcategory: Val) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1932087-73-4
- MDL: No data
- InChIKey: KSDLNKHXKRYOST-SFHVURJKSA-N
- Molecular Weight: 337.375
- Molecular Formula: C20H19NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbut-3-enoic acid
- SMILES: C=C([C@@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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